Buy O-DSMT

Buy O-DSMT – Premium Research Chemical for Advanced Opioid and Neuroscience Studies

Discover high-quality Buy O-DSMT (O-Desmethyltramadol) formulated for scientific research and analytical applications. This potent active metabolite of tramadol provides researchers with consistent potency and reliability in mu-opioid receptor studies, analgesic mechanism investigations, and opioid pharmacology. When you Buy O-DSMT, you get a versatile high-purity material (powder or pellets) that supports accurate dosing and reproducible experimental results in controlled laboratory environments.

Buy O-DSMT is widely sought by researchers exploring opioid receptor binding, metabolite activity, and structure-activity relationships due to its significantly higher mu-opioid affinity compared to the parent compound tramadol.

Chemical Components and Synonyms of O-DSMT

O-DSMT (O-Desmethyltramadol), also known as desmetramadol, is the primary active metabolite of tramadol. It features a cyclohexanol core with a dimethylaminomethyl group and a phenolic hydroxyl group.

Key Synonyms:

• O-Desmethyltramadol
• Desmetramadol
• O-DSMT
• M1 (tramadol metabolite)
• 3-[2-[(Dimethylamino)methyl]-1-hydroxycyclohexyl]phenol

These synonyms are commonly used when researchers search to Buy O-DSMT for laboratory investigations.

CAS Number: 144830-14-8 (free base); 80456-81-1 (hydrochloride salt)

Molecular Formula: C₁₅H₂₃NO₂ Molecular Weight: 249.35 g/mol

Molecular Structure of O-DSMT

The structure consists of a 1-(3-methoxyphenyl)-2-(dimethylaminomethyl)cyclohexanol framework with O-demethylation at the meta position, yielding a free phenolic hydroxyl group. This modification dramatically increases mu-opioid receptor affinity compared to tramadol. The hydrochloride salt form is commonly used for improved stability and solubility in research settings when you Buy O-DSMT.

Purity and Grade of O-DSMT

Reputable suppliers offer Buy O-DSMT at ≥98% purity, verified by HPLC, NMR, and MS analysis. Research-grade material meets stringent standards for analytical and preclinical use, delivering excellent batch-to-batch consistency. Always request Certificates of Analysis (COA) when purchasing Buy O-DSMT to ensure quality for your experiments.

Physical and Chemical Properties

O-DSMT typically appears as a white to off-white crystalline powder or in compressed pellet form. The hydrochloride salt offers good water solubility and solubility in organic solvents such as DMSO, ethanol, and methanol. It is stable under proper storage conditions with a relatively high melting point, making it suitable for precise laboratory weighing and solution preparation.

Safety and Handling of O-DSMT

Handle Buy O-DSMT exclusively in controlled laboratory settings using appropriate personal protective equipment (gloves, lab coat, safety goggles). Avoid inhalation, ingestion, or skin contact. Work in well-ventilated areas or fume hoods. Consult the Safety Data Sheet (SDS) for detailed toxicological information and follow standard chemical safety protocols.

Critical Note: This product is strictly for research and analytical purposes only. Not for human or veterinary consumption. O-DSMT is a potent opioid agonist with high risk of respiratory depression.

Usage and Applications

Researchers Buy O-DSMT primarily for studying mu-opioid receptor agonism, analgesic mechanisms, opioid metabolism, and comparative pharmacology with tramadol and other opioids. Applications include receptor binding assays, behavioral models of analgesia, pharmacokinetic studies, analytical method development, and investigations into opioid tolerance and dependence. As the main active metabolite responsible for much of tramadol’s effects, O-DSMT is a critical reference compound in opioid research.

Storage Conditions

Store Buy O-DSMT in a cool, dry place away from light and moisture. Recommended temperatures are 2-8°C or lower in airtight containers for long-term stability. Proper storage preserves compound purity and prevents degradation, ensuring optimal performance for ongoing research projects.

Regulatory Information

O-DSMT (desmetramadol) is a research chemical with varying legal status globally. It is often controlled or monitored as an opioid-related substance in many jurisdictions. Always verify and comply with local, national, and international regulations before acquiring Buy O-DSMT. This material is intended solely for qualified researchers and authorized institutions.

Shipping Information

Trusted vendors provide compliant, discreet shipping for Buy O-DSMT where legally permitted. Orders use secure packaging to maintain product integrity during transit. Contact suppliers for specific domestic and international shipping policies, documentation, and restrictions.

Technical Support and Contact Information

Leading research chemical suppliers offer dedicated technical support for product specifications, COAs, usage guidance, and custom inquiries. Reach out via email, live chat, or website forms for assistance with Buy O-DSMT orders or research questions.

Product Details

• Form: High-purity powder or precision pellets
• Purity: ≥98%
• Appearance: White to off-white crystalline solid
• Intended Use: Laboratory research and analytical applications only

FAQ About O-DSMT

What is O-DSMT? O-DSMT (O-Desmethyltramadol) is the primary active metabolite of tramadol and a potent mu-opioid receptor agonist used in opioid research.

Why is O-DSMT stronger than tramadol? It has significantly higher affinity for mu-opioid receptors, accounting for most of tramadol’s analgesic effects.

What is the difference between O-DSMT and tramadol? O-DSMT is the O-demethylated active form, while tramadol requires metabolic activation via CYP2D6.

How should O-DSMT be stored? In airtight containers in a cool, dark, dry place, preferably refrigerated or frozen for long-term stability.

Is O-DSMT legal for research? Availability depends on jurisdiction. Sold strictly for research purposes where permitted—always check local laws.

What solvents dissolve O-DSMT? It dissolves well in water (as HCl salt), DMSO, ethanol, and methanol; follow validated protocols for your assays.

This comprehensive guide on Buy O-DSMT supports researchers seeking reliable, high-purity opioid metabolite materials for neuroscience, pharmacology, and analgesic studies. Prioritize safety, regulatory compliance, and quality sourcing for all research chemical needs. For bulk orders, custom formulations, or additional documentation, connect with specialized laboratory suppliers.